Introduction to pharmacokinetics

Introduction to Pharmacokinetics

One of the most interesting and challenging aspects of early phase clinical trials is studying the pharmacokinetics of a new drug, in order to determine how a body processes it. For those readers with limited knowledge of the subject, this article is intended to provide an overview of pharmacokinetics, and the pharmacokinetic terms that are commonly used in medical journals. The article will al...

A short introduction to pharmacokinetics.

Phamacokinetics is proposed to study the absorption, the distribution, the biotransformations and the elimination of drugs in man and animals. A single kinetic profile may be well summarized by Cmax, Tmax, t 1/2 and AUC and, having more than one profile, 8 parameters at least, the mean and standard deviation of these parameters, may well summarize the drug kinetics in the whole population. A mo...

An Introduction to Sociolinguistics

Introduction to circular data

In many diverse scientific fields, the measurements are directions. For instance, a biologist may be measuring the direction of flight of a bird or the orientation of an animal. A series of such observations is called ”directional data”. Since a direction has no magnitude, these can be conveniently represented as points on the circumference of a unit circle centered at the origin or as unit ...

Introduction to Ethics

  The issues involved in this article are mainly concentrated on the origins of ethics or Moral ethics as an indepent science It has been said that this area of science was founded by Greek Philosophers after a great crisis and debates between such thinkers as Socrates, Plato and Aristotle on one side and  study of other cuitures and moral traditions, especially the Chinese and Hindu tradition...